Quality level: 200
Agency / Method
- meets BP analytical specifications
- meets the analytical specifications of Ph. Eur.
Form: viscous liquid
Quality: meets the analytical specification of Ph. Eur., BP
Application(s): Infrared spectroscopy: suitable
- acidity or alkalinity meets
- aromatic polycyclic. hydrocarbons comply
- residual solvents comply
- solid paraffin meet
Dynamic viscosity: 110-230 mPa.s
Density: 0.827-0.890 g / mL at 20 ° C
- complies with reaction against H2SO4
- according to identity (IR)
Article number 18512-4X2.5L will be discontinued. Order the 18512-2.5L single bottle which is physically identical with the exact same specifications. Article number 18512-6X1L will be discontinued. Order the individual bottle 18512-1L which is physically identical with the exact same specifications.
Long-term exposure to liquid paraffin to combat constipation can lead to exogenous lipoid pneumonia, especially in the chronically aspirated elderly. The condition is often overlooked in medical history. Other exposure contexts include the nasal or pharyngeal application of mineral oil and the compulsive use of lipsticks. The non-degradable mineral oil accumulates in the alveoli, where it causes a pulmonary reaction with fibrosis.
Exogenous lipoid pneumonia has a predilection for lung bases, or it may be a diffuse shading that, on HRCT, assumes a ground glass or crazy pavement appearance. Opacities exhibit low attenuation numbers and may exhibit the “spontaneous angiogram” sign. The surface of BAL appears oily to the naked eye and, microscopically, contains increased numbers of lymphocytes and/or neutrophils in addition to the characteristic vacuolated lipid-laden macrophages.
The diagnosis of exogenous lipoid pneumonia is based on the history and examination of sputum or BAL, which shows lipid-loaded cells and floating oil that stains positively for oil red-O and Sudan black. Lung biopsy is not indicated for the diagnosis of this condition, except perhaps to diagnose paraphinoma, a solitary mass of exogenous lipoid pneumonia that can be mistaken for lung cancer. Not all patients with exogenous lipoid pneumonia will improve after stopping oil and corticosteroid therapy.
Liquid paraffin interactions
Tell your doctor about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements. In particular, tell your doctor if you take vitamins. This product can interfere with the absorption of fat-soluble vitamins.
Liquid paraffin precautions
Serious side effects have been reported with this product, including the following:
- Paraffin anal leak with anal irritation after using this product for a long time.
- The granulomatous reaction caused by the absorption of small amounts of liquid paraffin.
- Lipoid pneumonia (accidental inhalation) can occur, so caution is required in patients with difficulty swallowing.
Contact your doctor if:
- you need a laxative every day
- have stomach pain that does not go away
- have a condition that makes swallowing difficult
This product is not recommended for children under 3 years of age.